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The leader of the REMEDIES Commercial Supply Chain says the pharmaceutical industry is on the cusp of a huge change.
Speaking to Research Horizons magazine, the Head of the Centre for International Manufacturing at Cambridge University, Dr Jag Srai, says the advent of continuous manufacturing combined with digital technologies are transforming supply chains through flexible production and automation, using sensors to track location, quality and authenticity, and using big data analytics on consumption patterns.
Dr Srai predicts that one of the big impacts for patients will be in using technology – matched with new approaches to manufacturing – to help people take their medicines every time they need to, perhaps at a dose that exactly matches their condition on that day:
“As in the world of e-commerce, we are at the early stages of understanding how this consumer and patient data can inform the supply chain,” says Jag. “But we can now contemplate scenarios in certain therapeutic areas, in which each dose a patient takes is fully optimised for the here and now, and manufactured continuously, or even printed on demand.”
Or in Research Horizon’s magazine (page 31) http://www.cam.ac.uk/system/files/issue_33_research_horizons.pdf
Crystec and Juniper Pharma Services are working together as part of the Advanced Manufacturing Supply Chain Initiative (AMSCI) project, ReMediES. Juniper Pharma Services will bring its expertise in characterisation, formulation development and GMP production to the supercritical fluid (SCF) manufacturing platform, ultimately reshoring this high value manufacturing process to the United Kingdom.
Read the full press release here: http://www.juniperpharma.com/juniper-and-crystec-sign-agreement-for-next-generation-medicines/.
Following the recent release of capital spend and funds for recruitment, a full Remedies consortium partner meeting was held at the IfM Cambridge to review progress on individual project workstreams and agree forward plans.
The review meeting included workstream presentations, break-out sessions evaluating emerging opportunities and cross-project linkages, and feedback from external advisors. The full partner meeting followed separate steering group and workstream leaders’ meetings earlier in the week as well as several individual workstream meetings held at the IfM. External advisors complimented the team on the progress made and on the organisation and review structures for this multi-workstream, multi-strand activity. Prospective partners Johnson Matthey and AMT joined the meeting to discuss the proposed new workstream on ‘enzymes in flow’. A key issue was how to link up with other relevant stakeholders beyond the Remedies project as keen interest from other pharmaceutical firms was noted, particularly in relation to the platform projects and selected application workstreams.
The next meeting of the full partner group will be held at the new Technology Innovation Centre, part of the CMAC University of Strathclyde facilities, in Glasgow, March 2016.
The REMEDIES (RE-configuring MEDIcines End-to-end Supply) project has accelerated into its next phase following the approval of £11.2m of government funding. The project is further strengthened by an £11m contribution from industry, matching the figure raised through Round 4 of the Advanced Manufacturing Supply Chain Initiative (AMSCI).