Home » Research » Project Structure » Workstream (App) “C” – Super Critical Fluids

Workstream (App) “C” – Super Critical Fluids


Worksteam Leader

Catherine Hunter, Crystec

Work Stream Objectives                       

Establish high value manufacturing facility in UK (re-shoring from China).

Explore supply chain benefits of using SCF to optimise drug substance physical form and eliminate variability early in development.

Explore potential of SCF technology to enable flexibility of scale and location, whilst enhancing product quality and reducing costs.

Demonstrate potential to generate functional particles and simplified formulations which reduce or eliminate the use of excipients.

­Programme will focus on proving concept through three product development programmes and assembling supporting data to demonstrate the supply chain, quality and excipient cost benefits of SCF technology.

Strands summary

Supercritical fluid (SCF) processing rig: Manufacture and assembly, Commissioning

Particle engineering

Knowledge transfer